Screening of Selected Asian Spices for Anti Obesity-related Bioactivities

Nancy Dewi Yuliana, Muzamal Iqbal, Muhammad Jahangir, Christofora Hanny Wijaya, Henrie Korthout, Marijke Kottenhage, Hye Kyong Kim, Robert Verpoorte

(Food Chemistry 126)


The potential health effects of 30 spices, commonly used for daily consumption, were submitted to bioactivity screening with several anti-obesity related bioassays: adenosine A1 receptor binding, cannabinoid CB1 receptor binding, TNF-a and 3T3-L1 adipocytes differentiation induction. Sesame seed and red chilli exhibited high binding activity to the adenosine A1 receptor and nutmeg, mace, black pepper and turmeric to the cannabinoid CB1 receptor, while piment and turmeric showed high inhibition of TNF-a accumulation. Black onion seed proved to be the only spice with high 3T3-L1 adipocyte differentiation induction activity. Several well known major compounds found in these active spices were tested with the respective bioassays but did not show activity. Thus, it appears that other minor compounds or the synergistic effects of different constituents are responsible for the observed activity.

2010 Elsevier Ltd. All rights reserved.

12,990 Responses to “Screening of selected Asian spices for anti obesity-related bioactivities”

  1. nuri said:

    very nice comment.

  2. Porn Service in North York said:

    This web site has been enthusiastically reviewed by a neighbor. So I decided that I should surf by and have a look. Good decision!

  3. asdasd said:


  4. asdasd said:


  5. vps satın al said:

    vps satın al

  6. wagga dentist said:

    Thank you, I’ve just been searching for information about this topic for a while and yours is the greatest I’ve discovered till now. But, what in regards to the conclusion? Are you sure concerning the supply?wagga dentist

  7. noor said:

    Thanks for this Useful blog
    improve your Knowledge

  8. dyana said:

  9. Rezheen said:

    Thanks for this Useful blog
    improve your Knowledge

  10. noor h said:


Leave a Reply